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Meet Len...
Len is an IT consultant. He has been happily married to wife Diane for 30 years. Len travels frequently for business and leisure, but the stress of travelling has made his psoriasis flare up.
“I’ve been watching what I
eat and drink recently,
but my psoriasis is as
bad as it’s always been.”
Age
67
Occupation
IT consultant.
Key consideration
Comorbidities and contraindications.
Medical history
Len has a BMI of 30 and suffers with high cholesterol. He was also diagnosed with moderate liver disease 3 years ago.
Len’s psoriasis
Len has had psoriasis, which mostly affects his face and neck, for most of his life. He was diagnosed with moderate-to-severe psoriasis aged 22.
Len has been treated with topicals and phototherapy, but recently he has started to experience frequent flare-ups.
Treatment options
Systemic therapy is suitable under NICE guidelines, but Len’s liver disease means he cannot take some of these treatments. Skilarence® (dimethyl fumarate) can be used in patients with moderate liver disease, without the need for dose adjustment. NICE guidelines recommend the use of Skilarence® when other systemic non-biological therapies cannot be taken.
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NICE treatment recommendations1
Systemic non-biological therapies should be used for people with moderate-to-severe plaque psoriasis if it cannot be controlled with topical therapy
AND
it has a significant impact on physical, psychological or social well-being
AND
any of the following apply:
Psoriasis is extensive.
For example, >10% of BSA
affected or PASI score of >10
Psoriasis is localised and
associated with significant functional impairment and/or high levels of distress (e.g. involvement at high-impact sites)
Phototherapy has been ineffective, cannot be used or has resulted in rapid relapse (>50% of baseline disease severity within 3 months)
If you have any questions, our representatives are on hand for further information about Skilarence®.
BSA, body surface area. DLQI, Dermatology Life Quality Index.
NICE, National Institute of Health and Care Excellence.
PASI, Psoriasis Area Severity Index. PGA, Physician Global Assessment.
Reference: 1. NICE. Psoriasis assessment and management (CG153). 2012. Available at: https://www.nice.org.uk/guidance/cg153.
Related
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UK-IEDMF-2100002
March 2021
Meet Len...
Len is an IT consultant. He has been happily married to wife Diane for 30 years. Len travels frequently for business and leisure, but the stress of travelling has made his psoriasis flare up.
Age: 67
Occupation: IT consultant.
Key consideration: Comorbidities and contraindications.
Len’s psoriasis
Len has had psoriasis, which mostly affects his face and neck, for most of his life. He was diagnosed with moderate-to-severe psoriasis aged 22.
Len has been treated with topicals and phototherapy, but recently he has started to experience frequent flare-ups.
Medical history
Len has a BMI of 30 and suffers with high cholesterol. He was also diagnosed with moderate liver disease 3 years ago.
Treatment options
Systemic therapy is suitable under NICE guidelines, but Len’s liver disease means he cannot take some of these treatments. Skilarence® can be used in patients with moderate liver disease, without the need for dose adjustment. NICE guidelines recommend the use of Skilarence® when other systemic non-biological therapies cannot be taken.