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Meet Caroline...

Caroline has been married to Thom for 15 years and they have a teenage daughter together. She used to enjoy being an active member of her local choir, but since her psoriasis has progressed, she no longer enjoys the social aspect. She has become reclusive – avoiding social interactions with her friends and no longer taking part in the activities she once loved.

“I’m definitely at my happiest when I’m with my family because they’re already used to my skin.”

Age

40

Occupation

Call-centre operator.

Key consideration

High functional impairment.

Medical history

Caroline suffers from anxiety as a result of her psoriasis, which has put a significant strain on her mental well-being.

Caroline’s psoriasis

Caroline has suffered with psoriasis for more than a decade, having been diagnosed with moderate-to-severe plaque psoriasis aged 28. Caroline’s psoriasis affects high-impact areas: her hands, forearms and legs.

Caroline’s psoriasis is not controlled with topicals or phototherapy. She has also experienced adverse events with methotrexate.

Treatment options

Because of her lack of response to topicals and phototherapy, and the extremely large effect on her life, Skilarence® (dimethyl fumarate) could be a suitable treatment for her under NICE guidelines.

What treatment option would you choose for this patient?

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NICE treatment recommendations1

Systemic non-biological therapies should be used for people with moderate-to-severe plaque psoriasis if it cannot be controlled with topical therapy

AND

it has a significant impact on physical, psychological or social well-being

AND

any of the following apply:

Psoriasis is extensive.
For example, >10% of BSA
affected or PASI score of >10

Psoriasis is localised and
associated with significant functional impairment and/or high levels of distress (e.g. involvement at high-impact sites)

Phototherapy has been ineffective, cannot be used or has resulted in rapid relapse (>50% of baseline disease severity within 3 months)

If you have any questions, our representatives are on hand for further information about Skilarence®.

BSA, body surface area. DLQI, Dermatology Life Quality Index.
NICE, National Institute of Health and Care Excellence.
PASI, Psoriasis Area Severity Index.

Reference: 1. NICE. Psoriasis assessment and management (CG153). 2012. Available at: https://www.nice.org.uk/guidance/cg153.

Related

Have you met patients like these in your clinic?

See how Skilarence® can help more patients with psoriasis. Click on a patient to find out more.

UK-IEDMF-2100002

March 2021

“I’m definitely at my happiest when I’m with my family because they’re already used to my skin.”

Meet Caroline...

Caroline has been married to Thom for 15 years and they have a teenage daughter together. She used to enjoy being an active member of her local choir, but since her psoriasis has progressed, she no longer enjoys the social aspect. She has become reclusive – avoiding social interactions with her friends and no longer taking part in the activities she once loved.

Age: 40

Occupation: Call-centre operator.

Key consideration: High functional impairment.

Caroline’s psoriasis

Caroline has suffered with psoriasis for more than a decade, having been diagnosed with moderate-to-severe plaque psoriasis aged 28. Caroline’s psoriasis affects high-impact areas: her hands, forearms and legs.

Caroline’s psoriasis is not controlled with topicals or phototherapy. She has also experienced adverse events with methotrexate.

Medical history

Caroline suffers from anxiety as a result of her psoriasis, which has put a significant strain on her mental well-being.

Treatment options

Because of her lack of response to topicals and phototherapy, and the extremely large effect on her life, Skilarence® could be a suitable treatment for her under NICE guidelines.

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